Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

10p11.22

lncRNA

ZEB1-AS1 ( ENSG00000237036)

miRNA

hsa-miR-874-3p (MIMAT0004911)

mRNA

PIN1 (ENSG00000127445)

Disease

LUAD

FDR

2.65E-4

Reported as biomarkers
1

Circulating
0

Drug resistent
11

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 A      GAG   GG               5 hsa-miR-874-3p
           GCCAGG   CCC        UCCCGUC    
           CGGUCC   GGG        GGGGCGG    
target 5 A      A     AGGCGGCA       C 3 ZEB1-AS1
Start: 124  End: 144
Energy: -34.9 kcal/mol
Align Score: 0.000905
miRNA  3 AGCC    A          G         UC 5 hsa-miR-874-3p
              AGGG       GCCC    GUCCCG     
              UCCC       UGGG    CAGGGC     
target 5    C    GAGUAGC    AUUA      C  3 ZEB1-AS1
Start: 138  End: 158
Energy: -28.4 kcal/mol
Align Score: 0.009393
miRNA  3 A        GC C         C 5 hsa-miR-874-3p
           GCCAGGGA  C GGUCCC GU    
           CGGUCUCU  G CCAGGG CG    
target 5 C        AA C      A  C 3 ZEB1-AS1
Start: 149  End: 169
Energy: -32.5 kcal/mol
Align Score: 0.003166
miRNA  3 A                      GG         5 hsa-miR-874-3p
           GCC     AGGGAG     CCC  UCCCGUC    
           CGG     UCCCUU     GGG  AGGGCAG    
target 5 C   GGAGU      GAUGA   GA       G 3 ZEB1-AS1
Start: 262  End: 282
Energy: -35.2 kcal/mol
Align Score: 0.00141
miRNA  3 A                      GG         5 hsa-miR-874-3p
           GCC     AGGGAG     CCC  UCCCGUC    
           CGG     UCCCUU     GGG  AGGGCAG    
target 5 C   GGAGU      GAUGA   GA       G 3 ZEB1-AS1
Start: 360  End: 380
Energy: -35.2 kcal/mol
Align Score: 0.00146

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for ZEB1-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-874-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for PIN1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 10p11.22

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.