Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

21q22.11

lncRNA

LINC00649 ( ENSG00000237945)

miRNA

hsa-miR-1254 (MIMAT0005905)

mRNA

CCAR1 (ENSG00000060339)

Disease

LUSC

FDR

5.95E-8

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
miRNA  3' UGACGUCCGAGGUCGAAGGUCCGA 5' hsa-miR-1254
                          ||||||| 
target 5'  GAGCAGGUUCUGACUUCCAGGCA LINC00649
Start: 2220  End: 2227
Site type: 8mer-1a
Context++ Score: -0.468
RNAbybrid target site prediction
miRNA  3             A    C            A 5 hsa-miR-1254
           UGACG  UCCG  GGU GAA   GGUCCG    
           ACUGC  GGGC  CCA CUU   CCGGGC    
target 5 C     UG    AG   U   CUC      G 3 LINC00649
Start: 213  End: 233
Energy: -34.6 kcal/mol
Align Score: 0.002604
miRNA  3    A         U  GA       GA 5 hsa-miR-1254
           UG CGUCCGAGG  C   AGGUCC     
           GC GCAGGUUCC  G   UCCAGG     
target 5 G  G         UU AGA      G  3 LINC00649
Start: 115  End: 135
Energy: -34.5 kcal/mol
Align Score: 0.002867
miRNA  3    A      AG   GA                5 hsa-miR-1254
           UG CGUCCG  GUC     AGG   UCCGA    
           GC GCAGGC  CAG     UCC   GGGCU    
target 5 G  C      G    AGACC   CUC     G 3 LINC00649
Start: 2  End: 22
Energy: -31 kcal/mol
Align Score: 0.001822
miRNA  3 U                               A          A 5 hsa-miR-1254
           GACG  UC CGAG              GUCG    AGGUCCG    
           CUGC  AG GCUC              CAGC    UCCAGGU    
target 5 C    UU  U    AAGGUCACCGCUCU    CUGG       G 3 LINC00649
Start: 248  End: 268
Energy: -31.9 kcal/mol
Align Score: 0.005175
miRNA  3       U               A             A 5 hsa-miR-1254
           UGACG C CGA     GGUCG     AGG  UCCG    
           ACUGC G GCU     UCAGC     UCC  GGGC    
target 5 G     U U   AGCAA     GAGAC   GU    G 3 LINC00649
Start: 51  End: 71
Energy: -31.4 kcal/mol
Align Score: 0.009104

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for LINC00649

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-1254

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for CCAR1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 21q22.11

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.