Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

2q13

lncRNA

MIR4435-2HG ( ENSG00000172965)

miRNA

hsa-miR-296-3p (MIMAT0004679)

mRNA

ICAM1 (ENSG00000090339)

Disease

LUSC

FDR

3.44E-3

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 C       A     UG                  5 hsa-miR-296-3p
           CUCUCGG    GG  GGUUG       GGAG    
           GGGAGCC    CC  CCAAU       CCUC    
target 5 A       AGGG  UG     GGAACCA    C 3 MIR4435-2HG
Start: 106  End: 126
Energy: -33.4 kcal/mol
Align Score: 0.004988
miRNA  3 C       A     UG                  5 hsa-miR-296-3p
           CUCUCGG    GG  GGUUG       GGAG    
           GGGAGCC    CC  CCAAU       CCUC    
target 5 A       AGGG  UG     GGAACCA    C 3 MIR4435-2HG
Start: 396  End: 416
Energy: -33.4 kcal/mol
Align Score: 0.003072
miRNA  3                  U         G 5 hsa-miR-296-3p
           CCUC     UCGGAGG GGGUUGGGA    
           GGAG     AGCCUCU CCUGGCUCU    
target 5 U    CCACC       C         G 3 MIR4435-2HG
Start: 115  End: 135
Energy: -32.3 kcal/mol
Align Score: 0.007045
miRNA  3           A   G  UU     G 5 hsa-miR-296-3p
           CC UCUCGG GGU GG   GGGA    
           GG GGAGCC CCA CC   CCCU    
target 5 A  U      A   G  UCU    G 3 MIR4435-2HG
Start: 140  End: 160
Energy: -31.5 kcal/mol
Align Score: 0.009191
miRNA  3           A   G  UU     G 5 hsa-miR-296-3p
           CC UCUCGG GGU GG   GGGA    
           GG GGAGCC CCA CC   CCCU    
target 5 A  U      A   G  UCU    G 3 MIR4435-2HG
Start: 192  End: 212
Energy: -31.5 kcal/mol
Align Score: 0.005891

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for MIR4435-2HG

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-296-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for ICAM1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 2q13

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.