Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

2p22.2

lncRNA

CYP1B1-AS1 ( ENSG00000232973)

miRNA

hsa-miR-345-5p (MIMAT0000772)

mRNA

NTRK3 (ENSG00000140538)

Disease

LUSC

FDR

1.72E-5

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 C    G                         A          5 hsa-miR-345-5p
           UCGG   ACCUGA            UCCUC     GUCG    
           AGCC   UGGACU            AGGAG     CAGC    
target 5 C    AUG      CUGCCACAGUGA     GAAGG    A 3 CYP1B1-AS1
Start: 303  End: 323
Energy: -32.4 kcal/mol
Align Score: 0.004795
miRNA  3 C    G                         A          5 hsa-miR-345-5p
           UCGG   ACCUGA            UCCUC     GUCG    
           AGCC   UGGACU            AGGAG     CAGC    
target 5 C    AUG      CUGCCACAGUGA     GAAGG    A 3 CYP1B1-AS1
Start: 274  End: 294
Energy: -32.4 kcal/mol
Align Score: 0.004518
miRNA  3                     A      G 5 hsa-miR-345-5p
           CUCG GGACCUGAUCCU C    GUC    
           GAGC CUUGGAUUGGGA G    CGG    
target 5 G    G            U GGGA   A 3 CYP1B1-AS1
Start: 303  End: 323
Energy: -30.2 kcal/mol
Align Score: 0.00925
miRNA  3     GG                    5 hsa-miR-345-5p
           CUC  GAC CUGAUCCUCAGUCG    
           GAG  UUG GACUGGGGGUCGGC    
target 5 U   A    A              A 3 CYP1B1-AS1
Start: 382  End: 402
Energy: -35.4 kcal/mol
Align Score: 0.002747
miRNA  3     GG                    5 hsa-miR-345-5p
           CUC  GAC CUGAUCCUCAGUCG    
           GAG  UUG GACUGGGGGUCGGC    
target 5 U   A    A              A 3 CYP1B1-AS1
Start: 349  End: 369
Energy: -35.4 kcal/mol
Align Score: 0.002364

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for CYP1B1-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-345-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for NTRK3

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 2p22.2

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.