Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

3q29

lncRNA

LINC00969 ( ENSG00000242086)

miRNA

hsa-miR-491-5p (MIMAT0002807)

mRNA

NOTCH3 (ENSG00000074181)

Disease

LUSC

FDR

5.72E-11

Reported as biomarkers
0

Circulating
1

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3                  A          U A 5 hsa-miR-491-5p
           GGAG  UACCUUCCCA       GGGG G    
           CCUU  AUGGGAGGGU       CCCC C    
target 5 A    AU          AAGGCUG    C G 3 LINC00969
Start: 473  End: 493
Energy: -32.3 kcal/mol
Align Score: 0.003895
miRNA  3 G         U   AA     GA 5 hsa-miR-491-5p
           GAGUAC CU CCC  GGGGU     
           CUCAUG GA GGG  CCUCA     
target 5 G      U  U   GG     G  3 LINC00969
Start: 209  End: 229
Energy: -30.4 kcal/mol
Align Score: 0.007368
miRNA  3 G         U   AA     GA 5 hsa-miR-491-5p
           GAGUAC CU CCC  GGGGU     
           CUCAUG GA GGG  CCUCA     
target 5 G      U  U   GG     G  3 LINC00969
Start: 77  End: 97
Energy: -30.4 kcal/mol
Align Score: 0.007745
miRNA  3 G         U   AA     GA 5 hsa-miR-491-5p
           GAGUAC CU CCC  GGGGU     
           CUCAUG GA GGG  CCUCA     
target 5 G      U  U   GG     G  3 LINC00969
Start: 273  End: 293
Energy: -30.4 kcal/mol
Align Score: 0.009144
miRNA  3                   A         G      A 5 hsa-miR-491-5p
           GGAGUA    CCUUCCC      AGGG     UG    
           CUUCAU    GGAAGGG      UCCC     AC    
target 5 U      CUUA       GUUACG    AAUAA  A 3 LINC00969
Start: 214  End: 234
Energy: -29.3 kcal/mol
Align Score: 0.009567

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for LINC00969

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-491-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for NOTCH3

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 3q29

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.