Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

22q13.2

lncRNA

NDUFA6-AS1 ( ENSG00000237037)

miRNA

hsa-miR-1296-5p (MIMAT0005794)

mRNA

ERBB2 (ENSG00000141736)

Disease

OV

FDR

9.07E-6

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 CC   A                   U 5 hsa-miR-1296-5p
            UCU CCUCGG    UCCCGGGAU    
            GGA GGGGCC    GGGGCCCUG    
target 5  U          CAAG         G 3 NDUFA6-AS1
Start: 1335  End: 1355
Energy: -35.9 kcal/mol
Align Score: 0.003994
miRNA  3 C   U   U            AUU 5 hsa-miR-1296-5p
           CUC ACC CGGUCCC G GG      
           GAG UGG GCCGGGG C CC      
target 5 U   C   C       A G  G   3 NDUFA6-AS1
Start: 82  End: 102
Energy: -30.3 kcal/mol
Align Score: 0.008047
miRNA  3                             GAUU 5 hsa-miR-1296-5p
           CCUCUACC   UCGG      UCCCGG       
           GGAGAUGG   GGCC      GGGGCU       
target 5 G        UCA    AGUGUG      A    3 NDUFA6-AS1
Start: 353  End: 373
Energy: -33.2 kcal/mol
Align Score: 0.003754
miRNA  3                                   5 hsa-miR-1296-5p
           CCUCUA  CCU  C GGUCCCGG    GAUU    
           GGAGGU  GGA  G CCGGGGCU    CUGA    
target 5 G      AA   CA C        UCGA    A 3 NDUFA6-AS1
Start: 322  End: 342
Energy: -30.9 kcal/mol
Align Score: 0.009553
miRNA  3                             GAUU 5 hsa-miR-1296-5p
           CCUCUACC   UCGG      UCCCGG       
           GGAGAUGG   GGCC      GGGGCU       
target 5 G        UCA    AGUGUG      A    3 NDUFA6-AS1
Start: 154  End: 174
Energy: -33.2 kcal/mol
Align Score: 0.00165

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for NDUFA6-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-1296-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for ERBB2

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 22q13.2

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.