Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

10p11.23

lncRNA

SVIL-AS1 ( ENSG00000224597)

miRNA

hsa-miR-185-3p (MIMAT0004611)

mRNA

STIM1 (ENSG00000167323)

Disease

OV

FDR

4.33E-18

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3              U                   A 5 hsa-miR-185-3p
           CUG GUCUCCUU          CG GUCGGGG    
           GAC CGGGGGAA          GC CGGCCUU    
target 5 A   G        UUCUGGGAGU  G       G 3 SVIL-AS1
Start: 93  End: 113
Energy: -30.1 kcal/mol
Align Score: 0.00722
miRNA  3 CU                       A 5 hsa-miR-185-3p
            GGUC   UCCUUUCGGU CGGGG    
            CCAG   AGGGAAGCCA GCCUU    
target 5  C    GCA          C     C 3 SVIL-AS1
Start: 694  End: 714
Energy: -33.2 kcal/mol
Align Score: 0.004524
miRNA  3            UU             A 5 hsa-miR-185-3p
           CUGGU CUCC  UCGGUCG   GGG    
           GGCCA GAGG  GGCCAGC   UCC    
target 5 U     G    UC       GGA   A 3 SVIL-AS1
Start: 386  End: 406
Energy: -34.6 kcal/mol
Align Score: 0.003825
miRNA  3      UCU            C       5 hsa-miR-185-3p
           CUGG   CCUU   UCGGU GGGGA    
           GGCC   GGAA   AGCCA CCCCU    
target 5 C    C      UGC           U 3 SVIL-AS1
Start: 176  End: 196
Energy: -30 kcal/mol
Align Score: 0.008957
miRNA  3    G                     GA 5 hsa-miR-185-3p
           CU GUCUC CU  UUC GGUCGGG     
           GA UGGGG GG  AAG CCAGCCU     
target 5 A  G     U  GC   U       G  3 SVIL-AS1
Start: 72  End: 92
Energy: -26.6 kcal/mol
Align Score: 0.009782

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for SVIL-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-185-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for STIM1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 10p11.23

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.