Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

2p13.3

lncRNA

PCBP1-AS1 ( ENSG00000179818)

miRNA

hsa-miR-194-3p (MIMAT0004671)

mRNA

ARHGEF2 (ENSG00000116584)

Disease

OV

FDR

1.44E-3

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
miRNA  3'  GUCUAUUGUCGUCGGGGUGACC 5' hsa-miR-194-3p
                  |||    ||||||| 
target 5' AACAAGCUCAGGGCUCCCACUGA PCBP1-AS1
Start: 115  End: 122
Site type: 8mer-1a
Context++ Score: -0.439
miRNA  3'  GUCUAUUGUCGUCGGGGUGACC 5' hsa-miR-194-3p
                  |||    ||||||| 
target 5' AACAAGCUCAGGGCUCCCACUGA PCBP1-AS1
Start: 179  End: 186
Site type: 8mer-1a
Context++ Score: -0.424
miRNA  3'  GUCUAUUGUCGUCGGGGUGACC 5' hsa-miR-194-3p
                  |||    ||||||| 
target 5' AACAAGCUCAGGGCUCCCACUGA PCBP1-AS1
Start: 47  End: 54
Site type: 8mer-1a
Context++ Score: -0.457
miRNA  3'  GUCUAUUGUCGUCGGGGUGACC 5' hsa-miR-194-3p
                  |||    ||||||| 
target 5' AACAAGCUCAGGGCUCCCACUGA PCBP1-AS1
Start: 125  End: 132
Site type: 8mer-1a
Context++ Score: -0.438
miRNA  3'  GUCUAUUGUCGUCGGGGUGACC 5' hsa-miR-194-3p
                  |||    ||||||| 
target 5' AACAAGCUCAGGGCUCCCACUGA PCBP1-AS1
Start: 246  End: 253
Site type: 8mer-1a
Context++ Score: -0.408
RNAbybrid target site prediction
miRNA  3 GU  A UG          GA    5 hsa-miR-194-3p
            CU U  UCGUCGGGGU  CC    
            GA A  GGCAGCCCCG  GG    
target 5  C  C UG          GC  A 3 PCBP1-AS1
Start: 178  End: 198
Energy: -31.1 kcal/mol
Align Score: 0.006404
miRNA  3 GUCUA   U           CC 5 hsa-miR-194-3p
               UUG CGUCGGGGUGA     
               GAC GCAGCCCCACU     
target 5     A   U           C  3 PCBP1-AS1
Start: 349  End: 369
Energy: -32.4 kcal/mol
Align Score: 0.007256
miRNA  3 GUCUA   U           CC 5 hsa-miR-194-3p
               UUG CGUCGGGGUGA     
               GAC GCAGCCCCACU     
target 5     A   U           C  3 PCBP1-AS1
Start: 154  End: 174
Energy: -32.4 kcal/mol
Align Score: 0.006467
miRNA  3 GUCUA   U           CC 5 hsa-miR-194-3p
               UUG CGUCGGGGUGA     
               GAC GCAGCCCCACU     
target 5     A   U           C  3 PCBP1-AS1
Start: 87  End: 107
Energy: -32.4 kcal/mol
Align Score: 0.005361
miRNA  3 G    U    GU                    5 hsa-miR-194-3p
           UCUA UGUC  CGGG       GUG ACC    
           GGAU GCAG  GCCC       CAC UGG    
target 5 G    U    GU    ACCACCA   U   C 3 PCBP1-AS1
Start: 388  End: 408
Energy: -29.6 kcal/mol
Align Score: 0.009251

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for PCBP1-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-194-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for ARHGEF2

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 2p13.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.