Basic Info

Starting a new search ...

Basic Information for the CNV-ceRNA event

Cytoband

16p13.3

lncRNA

ERVK13-1 ( ENSG00000260565)

miRNA

hsa-miR-346 (MIMAT0000773)

mRNA

LIF (ENSG00000128342)

Disease

OV

FDR

4.17E-21

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' ucUC-CGUCCGUACGCCCGUCUGu 5' hsa-miR-346
            || ||: ||:||  ||||||| 
target 5' gcAGTGCGAGCGTGAAGGCAGACa 3' ERVK13-1
Start: 1341  End: 1364
Energy: -29.03 kcal/mol
Align Score: 164
miRNA  3' ucUC-CGUCCGUACGCCCGUCUGu 5' hsa-miR-346
            || ||: ||:||  ||||||| 
target 5' gcAGTGCGAGCGTGAAGGCAGACa 3' ERVK13-1
Start: 73  End: 96
Energy: -29.03 kcal/mol
Align Score: 164
miRNA  3' ucUC-CGUCCGUACGCCCGUCUGu 5' hsa-miR-346
            || ||: ||:||  ||||||| 
target 5' gcAGTGCGAGCGTGAAGGCAGACa 3' ERVK13-1
Start: 73  End: 96
Energy: -29.03 kcal/mol
Align Score: 164
miRNA  3' ucUC-CGUCCGUACGCCCGUCUGu 5' hsa-miR-346
            || ||: ||:||  ||||||| 
target 5' gcAGTGCGAGCGTGAAGGCAGACa 3' ERVK13-1
Start: 17  End: 40
Energy: -29.03 kcal/mol
Align Score: 164
TargetScan target site prediction
miRNA  3' UCUCCGUCCGUACGCCCGUCUGU 5' hsa-miR-346
                         ||||||| 
target 5' CAGUGCGAGCGUGAAGGCAGACA ERVK13-1
Start: 89  End: 96
Site type: 8mer-1a
Context++ Score: -0.413
miRNA  3' UCUCCGUCCGUACGCCCGUCUGU 5' hsa-miR-346
                         ||||||| 
target 5' CAGUGCGAGCGUGAAGGCAGACA ERVK13-1
Start: 89  End: 96
Site type: 8mer-1a
Context++ Score: -0.415
miRNA  3' UCUCCGUCCGUACGCCCGUCUGU 5' hsa-miR-346
                         ||||||| 
target 5' CAGUGCGAGCGUGAAGGCAGACA ERVK13-1
Start: 33  End: 40
Site type: 8mer-1a
Context++ Score: -0.427
miRNA  3' UCUCCGUCCGUACGCCCGUCUGU 5' hsa-miR-346
                         ||||||| 
target 5' CAGUGCGAGCGUGAAGGCAGACA ERVK13-1
Start: 89  End: 96
Site type: 8mer-1a
Context++ Score: -0.413
miRNA  3' UCUCCGUCCGUACGCCCGUCUGU 5' hsa-miR-346
                         ||||||| 
target 5' CAGUGCGAGCGUGAAGGCAGACA ERVK13-1
Start: 89  End: 96
Site type: 8mer-1a
Context++ Score: -0.415
RNAbybrid target site prediction
miRNA  3' U    G     AC  C         5' hsa-miR-346
           CUCC UCCGU  GC CGUCUGU    
           GGGG AGGCG  CG GCAGACG    
target 5' C    G     CC  C       C 3' ERVK13-1
Start: 38  End: 58
Energy: -33.6 kcal/mol
Align Score: 0.008726
miRNA  3'               A                 5' hsa-miR-346
           UCUC CGUC CGU CGC    CCGUCUGU    
           GGGG GCAG GCG GCG    GGCAGACA    
target 5' G    A    U   A   UGAA        G 3' ERVK13-1
Start: 67  End: 87
Energy: -37 kcal/mol
Align Score: 0.000832
miRNA  3'               A                 5' hsa-miR-346
           UCUC CGUC CGU CGC    CCGUCUGU    
           GGGG GCAG GCG GCG    GGCAGACA    
target 5' G    A    U   A   UGAA        G 3' ERVK13-1
Start: 67  End: 87
Energy: -37 kcal/mol
Align Score: 0.000777
miRNA  3'               A                 5' hsa-miR-346
           UCUC CGUC CGU CGC    CCGUCUGU    
           GGGG GCAG GCG GCG    GGCAGACA    
target 5' G    A    U   A   UGAA        G 3' ERVK13-1
Start: 11  End: 31
Energy: -37 kcal/mol
Align Score: 0.00025
miRNA  3'                       C      5' hsa-miR-346
           UCUCCG UCCGUA CGCCCGU  UGU    
           GGGGGC GGGCGU GCGGGCA  GCG    
target 5' G      G      C       CA   U 3' ERVK13-1
Start: 9  End: 29
Energy: -39 kcal/mol
Align Score: 0.000819

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for ERVK13-1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-346

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for LIF

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 16p13.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.