Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

3p25.3

lncRNA

GHRLOS ( ENSG00000240288)

miRNA

hsa-miR-346 (MIMAT0000773)

mRNA

LIF (ENSG00000128342)

Disease

OV

FDR

1.82E-3

Reported as biomarkers
0

Circulating
0

Drug resistent
1

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
miRNA  3'  UCUCCGUCCGUACGCCCGUCUGU 5' hsa-miR-346
                          ||||||| 
target 5'  GGUGGCUGAUCACCUGGCAGACA GHRLOS
Start: 251  End: 258
Site type: 8mer-1a
Context++ Score: -0.411
miRNA  3'  UCUCCGUCCGUACGCCCGUCUGU 5' hsa-miR-346
                          ||||||| 
target 5'  GGUGGCUGAUCACCUGGCAGACA GHRLOS
Start: 251  End: 258
Site type: 8mer-1a
Context++ Score: -0.411
miRNA  3'  UCUCCGUCCGUACGCCCGUCUGU 5' hsa-miR-346
                          ||||||| 
target 5'  GGUGGCUGAUCACCUGGCAGACA GHRLOS
Start: 50  End: 57
Site type: 8mer-1a
Context++ Score: -0.462
RNAbybrid target site prediction
miRNA  3 U                     G       5 hsa-miR-346
           CUCCGUCC GUA   CGC CC UCUGU    
           GGGGCAGG CGU   GUG GG GGACA    
target 5 U        A   CCA   A  A     U 3 GHRLOS
Start: 387  End: 407
Energy: -33.2 kcal/mol
Align Score: 0.006195
miRNA  3 U      CCG       GU   U 5 hsa-miR-346
           CUCCGU   UACGCCC  CUG    
           GAGGCA   AUGCGGG  GGC    
target 5 U      A         GU   U 3 GHRLOS
Start: 222  End: 242
Energy: -36.8 kcal/mol
Align Score: 0.001646
miRNA  3 U      CCG       GU   U 5 hsa-miR-346
           CUCCGU   UACGCCC  CUG    
           GAGGCA   AUGCGGG  GGC    
target 5 U      A         GU   U 3 GHRLOS
Start: 222  End: 242
Energy: -36.8 kcal/mol
Align Score: 0.003553
miRNA  3 U      CCG       GU   U 5 hsa-miR-346
           CUCCGU   UACGCCC  CUG    
           GAGGCA   AUGCGGG  GGC    
target 5 U      A         GU   U 3 GHRLOS
Start: 21  End: 41
Energy: -36.8 kcal/mol
Align Score: 0.001003

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for GHRLOS

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-346

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for LIF

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 3p25.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.