Basic Info
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Basic Information for the SNP-ceRNA event
Variation
rs11653951 chr17:34071392(C/T)
lncRNA
AC024610.2 ( ENSG00000279668)
miRNA
hsa-miR-1229-3p (MIMAT0005584)
mRNA
SORL1 (ENSG00000137642)
Population
EUR_YRI
FDR
4.38E-24
Reported as biomarkers
![]() Circulating |
![]() Drug resistent |
![]() Survival |
Binding Info
Altered binding affnity between reference and alternative allele
miRanda reference allele (gain)
miRNA 3' gacacccUCCCGUC-ACCACUCUc 5' hsa-miR-1229-3p | Start: 46 End: 69Energy: -20.64 kcal/mol Align Score: 163 |
miRanda alternative allele (gain)
miRNA 3' gacacCCUCCCGUC-ACCACUCUc 5' hsa-miR-1229-3p | Start: 46 End: 69Energy: -21.46 kcal/mol Align Score: 165 |
TargetScan reference allele (gain)
miRNA 3' GACACCCUCCCGUCACCACUCUC 5' hsa-miR-1229-3p | Start: 62 End: 69Site type: 8mer-1a Context++ Score: -0.43 |
TargetScan alternative allele (gain)
miRNA 3' GACACCCUCCCGUCACCACUCUC 5' hsa-miR-1229-3p | Start: 62 End: 69Site type: 8mer-1a Context++ Score: -0.425 |
RNAhybrid reference allele (loss)
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RNAhybrid alternative allele (loss)
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Functions
Dysregulated fucntions of SNP-ceRNA event
Hallmarks
Dysregulated hallmarks of SNP-ceRNA event
Network
The AC024610.2-associated ceRNA network which were dysregulated by rs11653951