Basic Info
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Basic Information for the SNP-ceRNA event
Variation
rs4591246 chr18:21828568(G/A)
lncRNA
MIR133A1HG ( ENSG00000265142)
miRNA
hsa-miR-21-5p (MIMAT0000076)
mRNA
STAT3 (ENSG00000168610)
Population
EUR_YRI
FDR
8.03E-4
Reported as biomarkers
![]() Circulating |
![]() Drug resistent |
![]() Survival |
Binding Info
Altered binding affnity between reference and alternative allele
miRanda reference allele (loss)
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miRanda alternative allele (loss)
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TargetScan reference allele (gain)
miRNA 3' AGUUGUAGUCAGACUAUUCGAU 5' hsa-miR-21-5p | Start: 75 End: 82Site type: 8mer-1a Context++ Score: -0.409 |
TargetScan alternative allele (gain)
miRNA 3' AGUUGUAGUCAGACUAUUCGAU 5' hsa-miR-21-5p | Start: 75 End: 82Site type: 8mer-1a Context++ Score: -0.411 |
RNAhybrid reference allele (loss)
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RNAhybrid alternative allele (loss)
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Functions
Dysregulated fucntions of SNP-ceRNA event
Hallmarks
Dysregulated hallmarks of SNP-ceRNA event
Network
The MIR133A1HG-associated ceRNA network which were dysregulated by rs4591246