Basic Info
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Basic Information for the SNP-ceRNA event
Variation
rs8135839 chr22:44139698(G/A)
lncRNA
AL031595.3 ( ENSG00000280434)
miRNA
hsa-miR-423-5p (MIMAT0004748)
mRNA
FAM3A (ENSG00000071889)
Population
GBR
FDR
2.40E-5
Reported as biomarkers
![]() Circulating |
![]() Drug resistent |
![]() Survival |
Binding Info
Altered binding affnity between reference and alternative allele
miRanda reference allele (gain)
miRNA 3' uuuCAGAGCGAGAGACGGGGAGu 5' hsa-miR-423-5p | Start: 43 End: 64Energy: -28.48 kcal/mol Align Score: 162 |
miRanda alternative allele (loss)
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TargetScan reference allele (gain)
miRNA 3' UUUCAGAGCGAGAGACGGGGAGU 5' hsa-miR-423-5p | Start: 57 End: 64Site type: 8mer-1a Context++ Score: -0.52 |
TargetScan alternative allele (gain)
miRNA 3' UUUCAGAGCGAGAGACGGGGAGU 5' hsa-miR-423-5p | Start: 57 End: 64Site type: 8mer-1a Context++ Score: -0.53 |
RNAhybrid reference allele (loss)
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RNAhybrid alternative allele (loss)
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Functions
Dysregulated fucntions of SNP-ceRNA event
Hallmarks
Dysregulated hallmarks of SNP-ceRNA event
Network
The AL031595.3-associated ceRNA network which were dysregulated by rs8135839