Basic Info
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Basic Information for the variation-ceRNA event
Variation
rs4759314 12:53968051(A/G)
lncRNA
HOTAIR ( ENSG00000228630)
miRNA
hsa-miR-331-3p (MIMAT0000760)
mRNA
HOXC11 (ENSG00000123388)
Tissues
Gastric cancer tissue
Disease
gastric cancer
Pubmed Id
Title
The association analysis of lncRNA HOTAIR genetic variants and gastric cancer risk in a Chinese population
Description
Functional experiments revealed the allele-specific effects on HOTAIR and HOXC11 expressions in gastric cancer tissues, of which HOTAIR and HOXC11 expressions of individuals carrying with AG genotype were much higher than those with AA genotype; similarly, the effects occurred in intronic promoter activities, of which the promoter activity of G allele was more pronounced than that of A allele.
Reported as biomarkers
![]() Circulating |
![]() Drug resistent |
![]() Survival |