Basic Info

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Basic Information for the variation-ceRNA event

Variation

rs920778  12:53966448(G/A)

lncRNA

HOTAIR ( ENSG00000228630)

miRNA

hsa-miR-331-3p (NA)

mRNA

HER2 ()

Tissues

gastric cancer tissue, (AGS, MGC803) cell lines

Disease

gastric cancer

Pubmed Id
Title

A Functional lncRNA HOTAIR Genetic Variant Contributes to Gastric Cancer Susceptibility

Description

The rs920778 C>T SNP located in the intronic enhancer region alters the activity of this regulatory element. This may lead to increased HOTAIR expression, which conferring the underlying mechanism of gastric cancer susceptibility.

Reported as biomarkers
43

Circulating

24

Drug resistent

100

Survival

Annotations

External Annotation for HOTAIR

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.