Basic Information
| LncRNA/CircRNA Name | circFNDC3B |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | Esophageal Cancer |
| ICD-0-3 | C15 |
| Methods | qPCR, RNAi, other |
| Sample | esophageal cancer tissues and cell lines (ECA109 and KYSE150) |
| Expression Pattern | up-regulated |
| Function Description | circFNDC3B was specifically up-regulated in esophageal cancer tissues. Esophageal cancer cell lines ECA109 and KYSE150 with decreased circFNDC3B expression by gene silencing showed inhibited proliferation, increased apoptosis, and weakened migration and invasion abilities. |
| Pubmed ID | 31949813 |
| Year | 2018 |
| Title | CircRNA circFNDC3B Promotes Esophageal Cancer Progression via Cell Proliferation, Apoptosis, and Migration Regulation |
External Links
| Links for circFNDC3B | GenBank HGNC NONCODE |
| Links for Esophageal Cancer | OMIM COSMIC |