Basic Information
| LncRNA/CircRNA Name | AC105461.1 |
| Synonyms | NA |
| Region | GRCh38_2:231978488-232015720 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR |
| Sample | colorectal cancer tissues, cell lines (SW620, SW480, HT29, HCT116, and Caco-2) |
| Expression Pattern | up-regulated |
| Function Description | As a result, we found that AC105461.1 overexpression reduced the percentage of CD133+ CD44+, whereas its knockdown increased the percentage of CD133+CD44+. |
| Pubmed ID | 28496335 |
| Year | 2017 |
| Title | Knockdown of a DIS3L2 promoter upstream long noncoding RNA (AC105461.1) enhances colorectal cancer stem cell properties in vitro by down-regulating DIS3L2 |
External Links
| Links for AC105461.1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |