Basic Information
| LncRNA/CircRNA Name | CCAT1 |
| Synonyms | CCAT1, CARLo-5, onco-lncRNA-40 |
| Region | GRCh38_8:127207382-127219268 |
| Ensemble | ENSG00000247844 |
| Refseq | NR_108049 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | oral squamous cell carcinoma |
| ICD-0-3 | C06.9 |
| Methods | qPCR |
| Sample | oral squamous cell carcinoma tissues |
| Expression Pattern | up-regulated |
| Function Description | CCAT1 was significantly overexpressed in 27% (16/60) of oral tumors. The results suggested that CCAT1 overexpression may sponge miR155-5p and let7b-5p, and may account for poor treatment response. |
| Pubmed ID | 28413645 |
| Year | 2017 |
| Title | Long non-coding RNA CCAT1 is overexpressed in oral squamous cell carcinomas and predicts poor prognosis |
External Links
| Links for CCAT1 | GenBank HGNC NONCODE |
| Links for oral squamous cell carcinoma | OMIM COSMIC |