Basic Information
| LncRNA/CircRNA Name | circ_036186 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | head and neck squamous cell carcinoma |
| ICD-0-3 | C76.0 |
| Methods | qPCR, Microarray, other |
| Sample | HNSCC tissues |
| Expression Pattern | up-regulated |
| Function Description | In addition, the expression levels of circRNA_036186 and tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, ? polypeptide (14?????) were identified to be significantly different. A competing endogenous RNA (ceRNA) network was constructed, consisting of 5 circRNAs, 385 miRNAs and 96 mRNAs. Furthermore, we predicted that miR??93b??p exerts a significant effect on 14?????, and was significantly associated with the Hippo signaling pathway in HNSCC. On the whole, these findings suggest that circRNA_036186 likely regulates 14????? expression by functioning as a ceRNA in the development and progression of HNSCC. |
| Pubmed ID | 30066847 |
| Year | 2018 |
| Title | Competing Endogenous RNA Analysis Reveals the Regulatory Potency of circRNA_036186 in HNSCC |
External Links
| Links for circ_036186 | GenBank HGNC NONCODE |
| Links for head and neck squamous cell carcinoma | OMIM COSMIC |