Basic Information
| LncRNA/CircRNA Name | circ8924 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qPCR, western blot, luciferase reporter assay, other |
| Sample | cervical cancer tissues and cell lines (SiHa and HeLa) |
| Expression Pattern | up-regulated |
| Function Description | CircRNA8924 is highly expressed in CC tissue and can be considered a competitive endogenous RNA of the miR-518d-5p/519-5p family to promote the malignant biological behavior of CC cells. It is suggested that it may serve as a new biomarker for CC diagnosis and disease progression and provide potential targets for targeted therapy. |
| Pubmed ID | 30007986 |
| Year | 2018 |
| Title | CircRNA8924 Promotes Cervical Cancer Cell Proliferation, Migration and Invasion by Competitively Binding to MiR-518d-5p /519-5p Family and Modulating the Expression of CBX8 |
External Links
| Links for circ8924 | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |