Basic Information
| LncRNA/CircRNA Name | circ_0128298 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular cancer |
| ICD-0-3 | NA |
| Methods | qPCR, Microarray, other |
| Sample | HCC tissues |
| Expression Pattern | up-regulated |
| Function Description | The expression levels of hsa_circ_0128298 in HCC were significantly higher than those of paratumorous tissues (P<0.001). Additionally, hsa_circ_0128298 was a diagnostic factor, with the area under the ROC curve of 0.668 (95% CI =0.503-0.794, P<0.001). The sensitivity and specificity values were 0.716 and 0.815, respectively. The AFP and hsa_circ_0128298 expression levels were independent prognostic factors. The overall survival of patients with low hsa_circ_0128298 expression was significantly higher than that of patients with high hsa_circ_0128298 expression. |
| Pubmed ID | 29849467 |
| Year | 2018 |
| Title | Screening Differential Circular RNA Expression Profiles Reveal That hsa_circ_0128298 Is a Biomarker in the Diagnosis and Prognosis of Hepatocellular Carcinoma |
External Links
| Links for circ_0128298 | GenBank HGNC NONCODE |
| Links for hepatocellular cancer | OMIM COSMIC |