Basic Information
| LncRNA/CircRNA Name | circ_0000520 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | PCR |
| Sample | Human GC cell lines MKN-45, BGC-823, MGC- 80 803 and AGS, The human gastric epithelial cell 84 line GES-1, gastric cancer tissues and corresponding samples, blood |
| Expression Pattern | down-regulated |
| Function Description | hsa_circ_0000520 was first found to be significantly down-regulated in gastric cancer tissues, plasma and gastric cancer cell lines compared with control cases. Clinicopathological features showed that hsa_circ_0000520 level in GC tissues was negatively associated with TNM stage and in GC plasma linked with CEA expression. Finally, a total of 9 miRNAs and 9 candidate mRNA were predicted to have an interaction with hsa_circ_0000520. |
| Pubmed ID | 29103021 |
| Year | 2017 |
| Title | Hsa_circ_0000520, a potential new circular RNA biomarker, is involved in gastric carcinoma |
External Links
| Links for circ_0000520 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |