Basic Information
| LncRNA/CircRNA Name | circ_104700 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | RT-PCR |
| Sample | paired tumor and adjacent non-tumorous tissues |
| Expression Pattern | down-regulated |
| Function Description | We also first demonstrated that the expression levels of hsa_circRNA_103809 (p<0.0001) and hsa_circRNA_104700 (p=0.0003) were significantly lower in colorectal cancer than in normal tissues. The expression level of hsa_circRNA_103809 was significantly correlated with lymph node metastasis (p=0.021) and tumor-node-metastasis stage (p=0.011), and the expression level of hsa_circRNA_104700 was significantly correlated with distal metastasis (p=0.036). The area under receiver operating characteristic curves of hsa_circRNA_103809 and hsa_circRNA_104700 were 0.699 (p<0.0001) and 0.616 (p<0.0001), respectively. |
| Pubmed ID | 28349836 |
| Year | 2017 |
| Title | Identification of differentially expressed circular RNAs in human colorectal cancer |
External Links
| Links for circ_104700 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |