Basic Information
| LncRNA/CircRNA Name | circ_001988 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | PCR |
| Sample | tumor tissues and adjacent normal mucosa |
| Expression Pattern | down-regulated |
| Function Description | The expression of hsa_circ_001988 was significantly correlated with differentiation (P<0.05) and perineural invasion (P<0.05). The area under ROC curve of hsa_circ_001988 was 0.788 (P<0.05). Those results indicate that hsa_circ_001988 may become a novel potential biomarker in the diagnosis of colorectal cancer and a potential novel target for the treatment of colorectal cancer, Compared with normal samples, the expression of hsa_circ_001988 was significantly down regulated |
| Pubmed ID | 26884878 |
| Year | 2017 |
| Title | Decreased expression of hsa_circ_001988 in colorectal cancer and its clinical significances |
External Links
| Links for circ_001988 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |