Basic Information
| LncRNA/CircRNA Name | circ_0001649 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular cancer |
| ICD-0-3 | NA |
| Methods | Reverse transcription, PCR, siRNA interference |
| Sample | HCC and paired adjacent liver tissues, hepatoma cell lines, HCC-LM3 and 61 MHCC-97L |
| Expression Pattern | down-regulated |
| Function Description | hsa_circ_0001649 expression was significantly downregulated in HCC tissues (p = 0.0014) based on an analysis of 89 paired samples of HCC and adjacent liver tissues and the area under the ROC curve (AUC) was 0.63. Furthermore, hsa_circ_0001649 expression was correlated with tumor size (p = 0.045) and the occurrence of tumor embolus (p = 0.017) in HCC. |
| Pubmed ID | 26600397 |
| Year | 2017 |
| Title | Hsa_circ_0001649: A circular RNA and potential novel biomarker for hepatocellular carcinoma |
External Links
| Links for circ_0001649 | GenBank HGNC NONCODE |
| Links for hepatocellular cancer | OMIM COSMIC |