Basic Information
| LncRNA/CircRNA Name | AC130710 |
| Synonyms | GACAT3, LINC01458, lncRNA-AC130710 |
| Region | GRCh38_2:16050427-16085801 |
| Ensemble | ENSG00000236289 |
| Refseq | NR_126559 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR etc. |
| Sample | gastric cancer tissues, cell lines (AGS, BGC-823, MGC-803, SGC-7901 etc.) |
| Expression Pattern | up-regulated |
| Function Description | AC130710 in gastric cancer was significantly higher. Its expression level was significantly associated with tumor size, tumor-node-metastasis (TNM) stages, and distal metastasis. miR-129-5p may play an important role in the downregulation of AC130710 in gastric cancer cells. These results indicated that lncRNA-AC130710 may be a potential tumor marker for gastric cancer prognosis. |
| Pubmed ID | 24969565 |
| Year | 2014 |
| Title | lncRNA-AC130710 targeting by miR-129-5p is upregulated in gastric cancer and associates with poor prognosis. |
External Links
| Links for AC130710 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |