Basic Information
| LncRNA/CircRNA Name | CCDC26 |
| Synonyms | CCDC26, RAM |
| Region | GRCh38_8:128634199-129683679 |
| Ensemble | ENSG00000229140 |
| Refseq | NR_130917 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | pancreatic cancer |
| ICD-0-3 | C25 |
| Methods | qPCR, RNAi, Western blot, Cell proliferation assay etc. |
| Sample | pancreatic cancer tissues, cell lines (AsPC-1, PANC-1, SW1990, BxPC-3, MIAPaca-2 and CFPAC-1) |
| Expression Pattern | up-regulated |
| Function Description | We found that the CCDC26 expression was significantly higher in PC tissues than in normal tissues. CCDC26 levels were correlated with tumor size, tumor number, and reduced overall survival (OS). Knockdown of CCDC26 expression by small interfering RNA significantly promoted growth arrest and apoptosis. |
| Pubmed ID | 27470572 |
| Year | 2016 |
| Title | Long noncoding RNA CCDC26 as a potential predictor biomarker contributes to tumorigenesis in pancreatic cancer. |
External Links
| Links for CCDC26 | GenBank HGNC NONCODE |
| Links for pancreatic cancer | OMIM COSMIC |