Basic Information
| LncRNA/CircRNA Name | CDKN2B-AS1 |
| Synonyms | NA |
| Region | GRCh38_9:21994778-22121097 |
| Ensemble | ENSG00000240498 |
| Refseq | NR_003529 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qPCR, Luciferase reporter assay, Western blot |
| Sample | tissue ,cell line (Etc1/E6E7,HeLa, C4-1, SiHa, Ca Ski cells) |
| Expression Pattern | up-regulated |
| Function Description | CDKN2B-AS1 is significantly upregulated in most of the tumor cancer cells, including cervical cancer |
| Pubmed ID | 30884187 |
| Year | 2019 |
| Title | Interference of the long noncoding RNA CDKN2B-AS1 upregulates miR-181a-5p/TGF?I axis to restrain the metastasis and promote apoptosis and senescence of cervical cancer cells. |
External Links
| Links for CDKN2B-AS1 | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |