Basic Information
| LncRNA/CircRNA Name | CERNA2 |
| Synonyms | competing endogenous lncRNA 2 for microRNA let-7b |
| Region | GRCh38_1:29554-31109 |
| Ensemble | |
| Refseq | NR_134505 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | RT-PCR |
| Sample | GC tissues,GC cell lines (SGC7901, MGC803, and BGC823) and normal gastric epithelium cells (GES-1) |
| Expression Pattern | up-regulated |
| Function Description | the up-regulation of CERNA2 is associated with malignant status and poor prognosis in patients with GC, and silencing CERNA2 expression inhibits gastric cancer cell growth and promotes cell apoptosis. |
| Pubmed ID | 31949664 |
| Year | 2018 |
| Title | LncRNA CERNA2 Is an Independent Predictor for Clinical Prognosis and Is Related to Tumor Development in Gastric Cancer |
External Links
| Links for CERNA2 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |