Basic Information
| LncRNA/CircRNA Name | CHL1-AS1 |
| Synonyms | NA |
| Region | GRCh38_3:363370-385795 |
| Ensemble | ENSG00000234661 |
| Refseq | NR_110739 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | endometrial cancer |
| ICD-0-3 | NA |
| Methods | qRT-PCR, Western blot, RIP |
| Sample | EC cell lines (HEC1-A, HEC1-B, AN3CA,Ishikawa) |
| Expression Pattern | up-regulated |
| Function Description | CHL1-AS1 regulated EC progression via targeting the miR-6076/CHL1 axis, offering new insight into treating EC. |
| Pubmed ID | 31736153 |
| Year | 2019 |
| Title | Long noncoding RNA CHL1-AS1 promotes cell proliferation and migration by sponging miR-6076 to regulate CHL1 expression in endometrial cancer |
External Links
| Links for CHL1-AS1 | GenBank HGNC NONCODE |
| Links for endometrial cancer | OMIM COSMIC |