Basic Information
| LncRNA/CircRNA Name | CPS1-IT1 |
| Synonyms | CPS1-IT1, CPS1-IT, CPS1IT, CPS1IT1, PRO0132 |
| Region | GRCh38_2:210617571-210619876 |
| Ensemble | ENSG00000280837 |
| Refseq | NR_002763 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | autophagy0 | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, Western blot |
| Sample | colorectal cancer tissues, cell lines (LoVo, SW620, SW480, LS174T, HCT116 and HT29) |
| Expression Pattern | down-regulated |
| Function Description | Expression of CPS1-IT1 was significantly decreased in CRC tissues and cell lines, and patients with low CPS1-IT1 expression had poor survival outcomes. |
| Pubmed ID | 29145177 |
| Year | 2017 |
| Title | LncRna CPS1-IT1 Suppresses Cell Proliferation, Invasion and Metastasis in Colorectal Cancer |
External Links
| Links for CPS1-IT1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |