Basic Information
| LncRNA/CircRNA Name | CRNDE |
| Synonyms | CRNDE, CRNDEP, LINC00180, NCRNA00180, PNAS-108, lincIRX5 |
| Region | GRCh38_16:54845189-54929189 |
| Ensemble | ENSG00000245694 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, Microarray, RIP, Western blotting etc. |
| Sample | cell lines (DLD1, HCT116, SW480, SW620, LoVo, LS174t, HT29) |
| Expression Pattern | up-regulated |
| Function Description | CRNDE is upregulated in CRC tissues and cell lines. High CRNDE expression is associated with poor prognosis in CRC patients. CRNDE upregulates the expression of Ras/MAPK signaling genes. |
| Pubmed ID | 28594403 |
| Year | 2017 |
| Title | Long noncoding RNA CRNDE stabilized by hnRNPUL2 accelerates cell proliferation and migration in colorectal carcinoma via activating Ras/MAPK signaling pathways |
External Links
| Links for CRNDE | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |