Basic Information
| LncRNA/CircRNA Name | CTD-2020K17.1 |
| Synonyms | NA |
| Region | GRCh38_17:45190931-45222222 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | Microarray, qPCR, Western blot, in vitro knockdown etc. |
| Sample | cell lines (SKOV3, OVCAR3,CAOV3,HO8910,HOSE ), HGSOC tissues |
| Expression Pattern | up-regulated |
| Function Description | CTD-2020K17.1 overexpression promoted migration, invasion, and proliferation of ovarian cancer cells, and CTD-2020K17.1 regulated the expression of CARD11. CTD-2020K17.1 is significantly upregulated in OMTs and ovarian cancer cell lines. It can promote the migration, invasion, and proliferation of ovarian cancer cells, and CARD11 is regulated by CTD-2020K17.1. |
| Pubmed ID | 29504606 |
| Year | 2017 |
| Title | CTD-2020K17.1, a Novel Long Non-Coding RNA, Promotes Migration, Invasion, and Proliferation of Serous Ovarian Cancer Cells In Vitro. |
External Links
| Links for CTD-2020K17.1 | GenBank HGNC NONCODE |
| Links for ovarian cancer | OMIM COSMIC |