Basic Information
| LncRNA/CircRNA Name | CTD-2357A8.3 |
| Synonyms | NA |
| Region | GRCh38_17:78617389-78632057 |
| Ensemble | ENSG00000267123 |
| Refseq | NR_110848 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | head and neck squamous cell carcinoma |
| ICD-0-3 | C76.0 |
| Methods | other |
| Sample | TCGA |
| Expression Pattern | up-regulated |
| Function Description | CTD-2357A8.3 had the highest fold-change and was significantly associated with poor overall survival in patients with HNSCC. Furthermore, CTD-2357A8.3 was associated with 'signaling pathways regulating stem cell pluripotency', 'proteoglycans in cancer', 'transcriptional misregulation in cancer' and 'chemokine signaling pathway'. Further analysis demonstrated that CTD-2357A8.3 acted as a 'sponge' in order to competitively adsorb miRNA to regulate the expression of target gene caveolin 1 (CAV1) in HNSCC. |
| Pubmed ID | 31807160 |
| Year | 2019 |
| Title | Integrated Analysis of lncRNA CTD-2357A8.3 Expression and Its Potential Roles in Head and Neck Squamous Cell Carcinoma |
External Links
| Links for CTD-2357A8.3 | GenBank HGNC NONCODE |
| Links for head and neck squamous cell carcinoma | OMIM COSMIC |