Basic Information
| LncRNA/CircRNA Name | AF113014 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR, Western blot etc. |
| Sample | liver cancer tissues, cell lines (SMMC7721, HepG2, SK-Hep1 and Huh7) |
| Expression Pattern | differential expression |
| Function Description | AF113014 is differentially expressed between HCC cell lines and normal hepatocytes. Furthermore, we discovered that AF113014 up-regulated Egr2 expression through interacting with miR-20a. |
| Pubmed ID | 28542387 |
| Year | 2017 |
| Title | LncRNA-AF113014 promotes the expression of Egr2 by interaction with miR-20a to inhibit proliferation of hepatocellular carcinoma cells |
External Links
| Links for AF113014 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |