Basic Information
| LncRNA/CircRNA Name | DGCR5 |
| Synonyms | NA |
| Region | GRCh38_22:18970514-18994628 |
| Ensemble | ENSG00000237517 |
| Refseq | NR_002733 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | laryngeal cancer |
| ICD-0-3 | C32 |
| Methods | qPCR, Western blot, Luciferase reporter assay, RNAi, RIP |
| Sample | laryngeal squamous cell carcinoma tissues,cell lines (Hep-2 and Hep-2R) |
| Expression Pattern | up-regulated |
| Function Description | We found that DGCR5 was upregulated and microRNA-506 (miR-506) was downregulated in Hep-2R cells |
| Pubmed ID | 30980388 |
| Year | 2019 |
| Title | DGCR5 promotes cancer stem cell-like properties of radioresistant laryngeal carcinoma cells by sponging miR-506 via Wnt pathway |
External Links
| Links for DGCR5 | GenBank HGNC NONCODE |
| Links for laryngeal cancer | OMIM COSMIC |