Basic Information
| LncRNA/CircRNA Name | DICER1-AS1 |
| Synonyms | DICER1-AS1??ICER1-AS |
| Region | GRCh38_14:95157645-95179933 |
| Ensemble | ENSG00000235706 |
| Refseq | NR_015415 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | osteosarcoma |
| ICD-0-3 | NA |
| Methods | qPCR, western blot, RIP etc. |
| Sample | cell lines (MG-63, U2OS, HOS, 143B, Saos-2) |
| Expression Pattern | up-regulated |
| Function Description | Results showed that lncRNA DICER1-AS1 was up-regulated in osteosarcoma cells using microarray analysis and RT-PCR. In summary, all the results conclude that DICER1-AS1 regulates the proliferation, invasion and autophagy of osteosarcoma via miR-30b/ATG5 axis, providing a novel insight for osteosarcoma tumorigenesis. |
| Pubmed ID | 29772430 |
| Year | 2018 |
| Title | LncRNA DICER1-AS1 promotes the proliferation, invasion and autophagy of osteosarcoma cells via miR-30b/ATG5 |
External Links
| Links for DICER1-AS1 | GenBank HGNC NONCODE |
| Links for osteosarcoma | OMIM COSMIC |