Basic Information
| LncRNA/CircRNA Name | DINO |
| Synonyms | NA |
| Region | GRCh38_6:36677609-36678559 |
| Ensemble | ENSG00000285244 |
| Refseq | NR_144384 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR |
| Sample | GC tissues,cell lines(BGC-823,MGC-803) |
| Expression Pattern | down-regulated |
| Function Description | It was manifested that DINO was significantly downregulated in GC tissues. Then, DINO was modulated by infecting LV-DINO or by LV-shRNA in BGC-823 and MGC-803 cells. |
| Pubmed ID | 30775800 |
| Year | 2019 |
| Title | Long noncoding RNA DINO (damage induced noncoding) represses the development of gastric cancer by modulating p21 and Bcl-2 Associated X Protein (Bax) expression. |
External Links
| Links for DINO | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |