Basic Information
| LncRNA/CircRNA Name | DLEU1 |
| Synonyms | NA |
| Region | GRCh38_13:50082171-50723236 |
| Ensemble | ENSG00000176124 |
| Refseq | NR_002605 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioblastoma |
| ICD-0-3 | NA |
| Methods | qRT-PCR, Western blot |
| Sample | GBM tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | DLEU1 was upregulated in GBM and DLEU1 knockdown significantly inhibited GBM cell proliferation and induced apoptosis. |
| Pubmed ID | 31713587 |
| Year | 2019 |
| Title | SP1-DLEU1-miR-4429 feedback loop promotes cell proliferative and anti-apoptotic abilities in human glioblastoma |
External Links
| Links for DLEU1 | GenBank HGNC NONCODE |
| Links for glioblastoma | OMIM COSMIC |