Basic Information
| LncRNA/CircRNA Name | DLEU2 |
| Synonyms | DLEU1, BCMS, BCMS1, DLB1, DLEU2, LEU1, LEU2, LINC00021, NCRNA00021, XTP2 |
| Region | GRCh38_13:49982552-50125720 |
| Ensemble | ENSG00000231607 |
| Refseq | NR_002612 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | pancreatic cancer |
| ICD-0-3 | C25 |
| Methods | qPCR, Luciferase reporter assay, RIP |
| Sample | PC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | In this study, we found that the DLEU2 level was substantially upregulated in PC tissues and PC cell lines, and significantly associated with poor clinical outcomes in PC patients. |
| Pubmed ID | 30838724 |
| Year | 2019 |
| Title | Silencing of DLEU2 suppresses pancreatic cancer cell proliferation and invasion by upregulating microRNA-455. |
External Links
| Links for DLEU2 | GenBank HGNC NONCODE |
| Links for pancreatic cancer | OMIM COSMIC |