Basic Information
| LncRNA/CircRNA Name | DLX6-AS1 |
| Synonyms | NA |
| Region | GRCh38_7:96955141-97014065 |
| Ensemble | ENSG00000231764 |
| Refseq | NR_015448 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal squamous cell carcinoma |
| ICD-0-3 | NA |
| Methods | qRT-PCR, RIP |
| Sample | ESCC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | cell proliferation and metastasis of ESCC cells could be inhibited via reducing DLX6-AS1 expression. Besides, DLX6-AS1 was regarded as an oncogene in ESCC. Furthermore, DLX6-AS1 acted as a competing endogenous RNA via sponging miR-577 in ESCC. |
| Pubmed ID | 32096208 |
| Year | 2020 |
| Title | Upregulation of long noncoding RNA DLX6-AS1 promotes cell growth and metastasis in esophageal squamous cell carcinoma via targeting miR-577 |
External Links
| Links for DLX6-AS1 | GenBank HGNC NONCODE |
| Links for esophageal squamous cell carcinoma | OMIM COSMIC |