Basic Information
| LncRNA/CircRNA Name | DLX6-AS1 |
| Synonyms | NA |
| Region | GRCh38_7:96955141-97014065 |
| Ensemble | ENSG00000231764 |
| Refseq | NR_015448 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | Ewing sarcoma |
| ICD-0-3 | NA |
| Methods | RT-PCR, Western blot |
| Sample | Ewing?? sarcoma tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | DLX6-AS1 expression was increased in the tissue sample and cells. DLX6-AS1 functioned as the sponge of miR-124-3p, and then miR-124-3p targeted the 3??UTR of CDK4 mRNA, forming the DLX6-AS1/miR-124-3p/CDK4 regulatory pathway. |
| Pubmed ID | 31737208 |
| Year | 2019 |
| Title | Long noncoding RNA DLX6-AS1 targets miR-124-3p/CDK4 to accelerate Ewing?? sarcoma |
External Links
| Links for DLX6-AS1 | GenBank HGNC NONCODE |
| Links for Ewing sarcoma | OMIM COSMIC |