Basic Information
| LncRNA/CircRNA Name | DNM3OS |
| Synonyms | DNM3OS, DNM3-AS1, MIR199A2HG |
| Region | GRCh38_1:172136531-172144794 |
| Ensemble | ENSG00000230630 |
| Refseq | NR_038397 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal squamous cell carcinoma |
| ICD-0-3 | NA |
| Methods | Microarray, qPCR etc. |
| Sample | ESCC tissues |
| Expression Pattern | up-regulated |
| Function Description | Based on the fold change, significance, and number of transcripts, three upregulated lncRNAs (RP11-334E6.12, DNM3OS, and RP11-150O12.6) and three downregulated lncRNAs (AC103563.9, RP11-7K24.3, and RP11-351J23.1) with only one transcript were chosen as candidates for further validation. The results of qRT-PCR were consistent with the RNA sequencing data. |
| Pubmed ID | 27449043 |
| Year | 2016 |
| Title | Transcriptome profiling of lncRNA and co-expression networks in esophageal squamous cell carcinoma by RNA sequencing. |
External Links
| Links for DNM3OS | GenBank HGNC NONCODE |
| Links for esophageal squamous cell carcinoma | OMIM COSMIC |