Basic Information
| LncRNA/CircRNA Name | DSCAM-AS1 |
| Synonyms | NA |
| Region | GRCh38_21:40383083-40385358 |
| Ensemble | ENSG00000235123 |
| Refseq | NR_038896 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qRT-PCR, Western blot |
| Sample | CRC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | We demonstrated that DSCAM-AS1 was aberrantly up-regulated in CRC to modulate the proliferation and metastasis of cancer cells. DSCAM-AS1 can also act as a ??eRNA??to regulate the CDKL1 expression via sponging the expression of miR-144-5p. |
| Pubmed ID | 31730864 |
| Year | 2019 |
| Title | LncRNA DSCAM-AS1 Promotes Proliferation, Migration and Invasion of Colorectal Cancer Cells via Modulating miR-144-5p/CDKL1 |
External Links
| Links for DSCAM-AS1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |