Basic Information
| LncRNA/CircRNA Name | EGFR-AS1 |
| Synonyms | NA |
| Region | GRCh38_7:55179750-55188934 |
| Ensemble | ENSG00000224057 |
| Refseq | NR_047551 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal squamous cell carcinoma |
| ICD-0-3 | NA |
| Methods | Western blot |
| Sample | ESCC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | Their data showed that EGFR-AS1 and ROCK1 were upregulated in ESCC and positively correlated.EGFR-AS1 may upregulate ROCK1 by sponging miR-145 to promote ESCC cell invasion and migration. |
| Pubmed ID | 31702393 |
| Year | 2019 |
| Title | LncRNA EGFR-AS1 Upregulates ROCK1 by Sponging miR-145 to Promote Esophageal Squamous Cell Carcinoma Cell Invasion and Migration |
External Links
| Links for EGFR-AS1 | GenBank HGNC NONCODE |
| Links for esophageal squamous cell carcinoma | OMIM COSMIC |