Basic Information
| LncRNA/CircRNA Name | EGFR-AS1 |
| Synonyms | NA |
| Region | GRCh38_7:55179750-55188934 |
| Ensemble | ENSG00000224057 |
| Refseq | NR_047551 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | renal cancer |
| ICD-0-3 | C64.9 |
| Methods | qPCR, Western blot, RIP , Microarray |
| Sample | ccRCC tissues,cell lines(786O, OSRC-2,KETR-3) |
| Expression Pattern | up-regulated |
| Function Description | EGFR-AS1 was significantly upregulated in RCC tissues |
| Pubmed ID | 30770799 |
| Year | 2019 |
| Title | Long noncoding RNA EGFR-AS1 promotes cell growth and metastasis via affecting HuR mediated mRNA stability of EGFR in renal cancer. |
External Links
| Links for EGFR-AS1 | GenBank HGNC NONCODE |
| Links for renal cancer | OMIM COSMIC |