Basic Information
| LncRNA/CircRNA Name | EIF3J-AS1 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | RT-qPCR, Western blot |
| Sample | CRC tissues,cell lines (HCT116, SW620, SW480, RKO) |
| Expression Pattern | up-regulated |
| Function Description | EIF3J-AS1 was upregulated by cAMP-response element-binding protein-binding protein-mediated histone H3 on lysine 27 acetylation (H3K27ac) at the promoter region, and EIF3J-AS1 upregulated YAP1 expression through sponging miR-3163 in CRC cells. |
| Pubmed ID | 31709617 |
| Year | 2019 |
| Title | H3K27 acetylation-induced lncRNA EIF3J-AS1 improved proliferation and impeded apoptosis of colorectal cancer through miR-3163/YAP1 axis |
External Links
| Links for EIF3J-AS1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |