Basic Information
| LncRNA/CircRNA Name | ELMO1-AS1 |
| Synonyms | NA |
| Region | GRCh38_7:36997796-37013630 |
| Ensemble | ENSG00000224101 |
| Refseq | NR_104120 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR, etc. |
| Sample | HCC tissues, human liver cancer cell lines, SMMC-7721 and HepG2 |
| Expression Pattern | down-regulated |
| Function Description | ELMO1-AS1 was significantly downregulated in HCC tissues, and high expression of ELMO1-AS1 is correlated with optimistic treatment outcome suggesting its potential as an independent prognostic biomarker for HCC. It was also found that overexpression of ELMO1-AS1 in HCC cells suppressed cell proliferation, migration and invasion and engulfment and cell motility 1 (ELMO1) may be a target of ELMO1-AS1. |
| Pubmed ID | 31498334 |
| Year | 2019 |
| Title | Macrophage-associated lncRNA ELMO1-AS1: a novel therapeutic target and prognostic biomarker for hepatocellular carcinoma |
External Links
| Links for ELMO1-AS1 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |