Basic Information
| LncRNA/CircRNA Name | ElncRNA1 |
| Synonyms | NA |
| Region | GRCh38_1:204141408-204143009 |
| Ensemble | ENSG00000230550 |
| Refseq | NR_123739 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | epithelial ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | qPCR, Western blot etc. |
| Sample | EOC tissues, cell lines (SKOV3, CAOV3, OVCAR3 and HO8910) |
| Expression Pattern | up-regulated |
| Function Description | E2 upregulates ElncRNA1 at the transcriptional level through the ERa-ERE pathway and that this novel E2-upregulated lncRNA has an oncogenic role in EOC growth. The placement of ElncRNA1 in the E2-ERa-ERE signalling pathway may provide greater insight into the effects of oestrogen on EOC progression from the perspective of lncRNA. |
| Pubmed ID | 28714515 |
| Year | 2017 |
| Title | ElncRNA1, a long non-coding RNA that is transcriptionally induced by oestrogen, promotes epithelial ovarian cancer cell proliferation. |
External Links
| Links for ElncRNA1 | GenBank HGNC NONCODE |
| Links for epithelial ovarian cancer | OMIM COSMIC |