Basic Information
| LncRNA/CircRNA Name | ENST00000602301 |
| Synonyms | VTRNA2-1, CBL-3, CBL3, MIR886, MIRN886, VTRNA2, hsa-mir-886, hvg-5, nc886, svtRNA2-1a |
| Region | GRCh38_5:136080470-136080597 |
| Ensemble | ENSG00000270123 |
| Refseq | NR_030583 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | EGFR-TKI | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung adenocarcinoma |
| ICD-0-3 | C34 |
| Methods | Microarray, qPCR etc. |
| Sample | cell lines (HCC827 and HCC827-8-1) |
| Expression Pattern | down-regulated |
| Function Description | To validate the results of the microarray, we chose a total of 7 differentially expressed lncRNA transcripts for RT-qPCR. The RT-qPCR results were consistent with that of the microarray, in that all 7 lncRNA transcripts were differentially expressed with the same trend (upregulated or downregulated) and reached statistical significance. |
| Pubmed ID | 27108960 |
| Year | 2016 |
| Title | Genome-wide profiling of long non-coding RNA expression patterns in the EGFR-TKI resistance of lung adenocarcinoma by microarray. |
External Links
| Links for ENST00000602301 | GenBank HGNC NONCODE |
| Links for lung adenocarcinoma | OMIM COSMIC |